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Making Lifesaving Cell Therapies Safer and More Accessible for All

Together, we will transform the lives of millions of people around the world by creating more potent and durable breakthrough cell therapies.

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Solving challenges with microfluidics

FASTER

FASTER

Getting effective treatments to patients quicker

By unlocking faster cell recovery, delivering higher yields, and simplifying manufacturing processes, cell therapy innovators can achieve radically shortened vein-to-vein times.

SCALABLE

SCALABLE

From millions to billions seamlessly

Cells move through the channels in an identical manner to ensure the highest quality of engineered cells at any scale – from millions to billions. Scale is elegantly achieved by increasing the number of channels from laboratory experiments to clinical, large-volume applications.

ACCESSIBLE

ACCESSIBLE

Lower costs to manufacture

Simplified workflows and unparalleled scalability provide significant time and cost efficiencies in the development and manufacturing of cell therapies, enabling the rapid and seamless transition from laboratory to clinical, large-volume applications.

EFFECTIVE

EFFECTIVE

Higher potency and durability of cell therapies

Reduced expansion time results in higher quality of manufactured cells and a higher percentage of stem memory cells – the best predictors of cell therapy success in the treatment of cancer.

THE TECHNOLOGY

A paradigm shift for cell therapy manufacturing

image shows three icons in progression. The first icon shows two cells being compressed with the text "ensures gentle cell processing" underneath. An arrow points to the second icon, which shows strands mRNA and payload being delivered into the cell with text underneath that reads "enables complex gene editing." A final arrow points to the last icon that shows cells stacking upward in a triangle shape, the text underneath reads "delivers high yields."

The CellFE technology produces the highest quality of edited cells – vital to advanced cell therapies. Cells recover rapidly to enable multiple sequential editing events, resulting in high yields of edited cells with exceptional proliferative capacity. 

How It Works

THE ADVANTAGE

Removing limitations to improve therapeutics outcomes

Our microfluidic process ensures rapid genome editing of cells in a manner that retains cell quality – eliminating risk of genotoxicity and chromosomal abnormalities. 

A graphic shows cells flowing under a chevron shaped ridge, where the cell is compressed, and then returning to their normal size after the ridge. Payload is shown being delivered inside the cell once it returns to size after the ridge.

Conventional manufacturing processes introduce unintended genetic mutations, posing greater risk to patients.

VIRAL TRANSDUCTION

A virus is shown with orange squiggles inside.

Random integration and insertional mutagenesis

ELECTROPORATION

a misshapen cell is shown with two lighting bolts at the top. The outer wall of the cell is breaking down.

Risk of genomic translocations

Changing the game in cell therapy workflows

Currently, best in class cell therapy workflows are achieved by deploying expensive, lengthy, and error-prone processes that span multiple unit operations.

We envision a future where treatments are produced point-of-care. With the CellFE microfluidic technology, simplicity of operation allows our partners to seamlessly integrate, scale up, down, and out, to enable expansion into decentralized, closer to the patient, point of care treatments.

Four icons are show with an arrow behind them pointing to the right. The first icon shows a cartoon of a woman symbolizing a patient. The second icon is a collection of cartoon cells and directs toward the third icon which is CellFE's instrument. The instrument directs toward the last icon, which shows the patient again. Under the cell and instrument icons is a bracket with text that says "1-2 days"
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Dedicated to helping our partners advance cell therapies

We combine decades of experience by bringing together a passionate, multidisciplinary team of experts with a single-minded focus to support our partners’ success. Working together, we will solve the challenges in expanding access to advanced cell therapies for all patients globally.

Four images surround a small circular wafer with many microfluidics chips on it. The top left image shows a female scientist sitting at a computer in a lab with flow results on the computer screen; the word Immunology appears in all caps at the bottom of the image. The top right image shows two scientists at a lab bench using CellFE instrument; the words "Cell Biology" appear in all caps at the bottom of the image. The bottom right image shows a scientist looking at a circular wafer under a microscope; the words Microfluidics appear in all caps at the bottom of the image. The bottom left image shows a man in a suit pointing at the instrument wiring as other colleagues look at where he is pointing; the word "Engineering" appears in all caps at the bottom of the image.
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